Tuesday, August 25, 2020

Physic Sc1 Resistance Of A Wire

Physic Sc1 Resistance Of A Wire How the obstruction of a wire changes with various lengths Planning We are attempting to see whether and how the opposition of a wire changes by altering the length of the wire. I feel that as the length builds; the opposition will likewise increment. I think this will happen on the grounds that in past analyses, my outcomes have demonstrated this. For instance: I have done an examination where I needed to discover what factors influenced the obstruction of a wire. I set up a circuit like the one in the outline underneath. In any case, rather than keeping all the factors the equivalent, I transformed them, each in turn, to perceive what impact they may have on the opposition of a wire.Predicted Graph Circuit Diagram The contraption I will utilize is: battery pack, drives, ammeter, constantan wire (0.25 mm), ruler, crocodile cut and a voltmeter.I did a viable in which I decided to utilize constantan wire.English: Four-wire setup of an obstruction t...

Saturday, August 22, 2020

Comprehensive Environmental Analysis Paper Free Essays

Running head: Comprehensive Environmental Analysis Paper Comprehensive Environmental Analysis Paper University of Phoenix August 31, 2009 Comprehensive Environmental Analysis Paper Despite the ongoing mishaps for its picture, the United States has by a long shot the biggest impact in the district. During 2007, China provided more than 66% of PCs sent out to the U. S. We will compose a custom article test on Exhaustive Environmental Analysis Paper or on the other hand any comparable subject just for you Request Now from the six significant exchanging countries. Truth be told, China added to $23. 2 billion (76. 7% ) of U. S. PC imports. It ought not, in any case, underestimate its impact in the area for without a doubt, if China is to keep on situating itself as an Asia Pacific force. Its impact in the district can't be kept up by financial and military matchless quality alone. East Asia is experiencing memorable geopolitical changes because of the ascent of China. Political enthusiasm for the vision of an East Asian people group proposes that the locale is looking for another request to suit China’s developing force and impact and to keep up local harmony and steadiness. Not the slightest bit is this a simple undertaking. Asian nations will in general experience the ill effects of local political challenges in monetary advancement, enormous holes in formative stages among territorial economies, and shared doubt and chronicled hostility among Japan and China. In spite of these troubles, in any case, there is a developing agreement that, in the end, East Asian nations will concoct some type of a local network. Territorial collusions and monetary mix East Asian financial coordination will help lessen provincial strain and help America’s security trouble in the area. Financial combination will connect with provincial powers in stable local relationship where one’s flourishing is in light of a legitimate concern for other people, and make them progressively unsurprising and solid to one another. Effective improvement of less fortunate nations in Asia through reconciliation in territorial financial dynamism will support political security and diminish the likelihood that these nations will become hotbeds of fear based oppression. Local: Physical condition and its impact on exchange Asia’s physical condition has a major effect on exchange several different ways. First the climate in Asia as a locale is entirely unusual. Having erratic climate or cataclysmic occasions can majorly affect a business since organizations could lose physical property, fabricating time, or items which would bring about money related misfortune. The air quality inside the urban communities of Asia is poor and is known for making medical problems among the people living around there. Creation can be influenced if workers are out debilitated and away from their employments. Air contamination and an unclean situation just to some degree impacts exchange; anyway an association can without much of a stretch open up a processing plant there also with modest work and feeble natural laws. Numerous remote organizations have set their manufacturing plants in China with a lot of progress due to the capacity to employ modest work and to run their industrial facilities without numerous guidelines. Provincial Political Stability The political steadiness of China appears to be dubious, best case scenario. â€Å"While the US depends on free markets and free social orders as the reason for contemporary financial and political development, China centers around steadiness as the pith of its remote policy† (Cheow, 2006). China has frequently been energized by purposeful publicity however as of late, China’s top political pioneers have started to pressure how significant solidness is with all individuals all through their nation. This incorporates all individuals from all foundations. China’s political soundness has assisted with filling financial development all through the nation. Local Social, Health, and Environmental Conditions Chinese specialists stay among the most reduced paid on the planet. The normal all out work remuneration for a Chinese assembling specialist is 57 pennies for each hour, with many creation far not as much as that, benefits included† (McCormack, 2006). This mea ns around $104 every month; this makes carrying on with a better than average life as we probably am aware it totally outlandishly. Some low-paid Chinese workers will live in filth and with numerous individuals to little single room quarters. In China there is no deficiency of laborers; China has a huge joblessness pace of 25% (McCormack, 2006) leaving a wealth of low arning workers for a long time to come. Provincial Terrorism Threats China has an inner fear monger danger. Not exclusively are there Muslim Separatists’ in the locale, yet additionally the Uygur dissident gatherings and the East Turkistan Islamic Movement, the two of which have â€Å"been rumored to have prepared in Afghanistan to battle alongside the Taliban and al Qaeda† (chinaguide,com, 2009). It is essential to comprehend China has perceived this issue and â€Å"to battle fear mongering, the Chinese government will improve global collaboration and fortify enactment and law requirement on hostile to terrorism† (Xinhua News Agency, 2005). Local: Economic conditions The monetary states of Asia contrast from which nation you are in. This can influence exchange numerous ways that are sure and negative. The positives that originate from a poor economy are the capacity to enlist modest work and to spend less on assembling the item. The organization likewise comes into the locale extending employment opportunities to a general public that really needs cash and the capacity to get by. Another preferred position is the capacity to trade items everywhere throughout the world from a beneficial area. Negative parts of a poor economy are that the item won't sell well in a poor area. Burglary and decimation to an association are another peril that could happen when situated in a poor district. The financial circumstances change; a few places in Asia are rich while some are exceptionally poor. Because of this reality, it is essential to tailor an associations showcasing system to those every particular zone. Local: Finance choices accessible When an association chooses to open their organization in Asia, it is basic to back through a monetary organization that is settled. Group B’s organization should back their worldwide association through a fruitful, settled bank. There are additionally numerous fruitful organizations in Asia that might help fund and put resources into Team B’s association. Making a solid colleague is critical in making a fruitful and dependable association. Nation Political soundness Since 1978 China has experienced a progression of fast changes inside their administration framework; these political changes length from human rights practices to new work laws. These new laws have permitted China to make a strong and stable establishment for the legislature and to work every day. At the present time, China is politically steady. This can be found in the development of China just as the effect that China is having on the worldwide market. Nation Economic Conditions In 1987, China built a three stage formative technique that would build the general monetary conditions in China. These three formative methodologies are: to twofold the 1980 GNP and guarantee that the individuals have enough food and apparel, to fourfold the 1980 GNP before the finish of the twentieth century, and to increment per-capita GNP to the degree of the medium-created nations constantly 2050. Stage one guarantees that the Chinese degree of destitution won't increment. The subsequent advance has just been accomplished in 1995. At last, the third and last advance, clarifies that by expanding the GNP, Chinese residents will be monetarily steady and be outfitted with present day innovation. The current monetary condition is superior to expected with new substantial and light industry, farming and vitality extension. The Chinese economy keeps on developing at a quick pace. Nation Financial Options Building and assembling plastic PC lodging in China offers several budgetary alternatives for the organization to extend. The principal monetary choice accessible is low to no intrigue credits offered by the Chinese government. This money related alternative is a motivating force offered by China to draw in new business into their nation. Another monetary alternative is building capital through financial specialists. This alternative would make a gathering of investors that have intvested the capital expected to construct another office with potential profit for their speculation. Nation Social, Health, and Environmental Conditions The present social, wellbeing and natural conditions are not comparable to different nations yet the Chinese government is taking a shot at changing these conditions all through the country. The security and working conditions are viewed as much lower and more perilous than different pieces of the world. A couple of the means that the Chinese government is right now taking a shot at are 1. â€Å"Enacting and improving condition and wellbeing laws and guidelines. † (China. organization. cn. , 2009). 2. â€Å"Build a management organize on condition and health† (China. organization. cn. , 2009). 3. â€Å"Set up state condition and wellbeing data offer and administration system† (China. organization. cn. , 2009). Despite the fact that China’s current social, wellbeing, and ecological conditions are not the most great, the Chinese government is consistently dealing with approaches to improve the nature of the earth and working conditions all through the country. Social Considerations One of the primary things that ought to be considered is that China’s history traverses over 5,000 years. In years past China has encountered times of feudalism, socialism, intrusion, however now they have a juvenile market economy. When considering working together in China, probably the greatest interesting point is the various varieties of Chinese business culture and manners. Chinese business culture and decorum incorporates keeping in touch between the individuals from the busin

Care for the Older Persons

Question: Examine about theCare for the Older Persons. Answer: Presentation The difficulties in the consideration for more seasoned people have overall viewpoint. It is important to comprehend the present changes in national and additionally worldwide segment patterns with respect to more established individuals. Focal Statistics Office in the PWC and Independent Health and Care Providers (2011) report show that the number of inhabitants in the elderly folks individuals in Ireland was 532, 000 and projections demonstrate conceivable shoot to 1.4 million by 2046. The expansion in future in Ireland and in other creating economies among other segment changes brings about the need to discover approaches to continue and advance the soundness of more established individuals. Understanding these socioeconomics can empower governments and deliberate consideration organizations to plan on the most proficient method to think about the old utilizing quality and adequate assets into what's to come. Among the elements that are as of now adding to the expansion in the num ber of inhabitants in more established individuals in Ireland and globally incorporate fundamentally, an increment in life span and a decrease in fruitfulness rates (Standard Poors, 2010). The fundamental reasons for life span incorporate improved medicinal services, better eating regimen, and consistence to social insurance plans including physical wellness among others (PWC and Independent Health and Care Providers, 2011). This introduction contains a conversation on the requirement for care of the old, the various jobs of social insurance suppliers, legal and volunteer organizations, the network and families under the watchful eye of the more established people. It additionally remembers an audit for the distinctive human services settings for the consideration of the matured, and the jobs of the medicinal services aides in advancing inspirational mentality towards the more seasoned people in the general public. Conversation Sound maturing alludes to the streamlining of chances accessible, for physical-social and even psychological wellness to push the matured to effectively take part in the general public with no separation while getting a charge out of autonomous and a decent personal satisfaction. Sound maturing in this way is dictated by the accessibility of a few components including sustenance, access to administrations, business/volunteer administrations, long haul care, condition, and utilization of most recent advancements (Standard Poors, 2010). Maturing presents with various physiological changes and these incorporate loss of teeth because of gum contaminations, tangible incitement misfortune prompting visual hindrance, deferred processing because of declined creation of stomach related juices, decrease in the usefulness of the musculoskeletal framework prompting joint inflammation and osteoporosis, dementia additionally creates among different conditions. Mental changes among the older then a gain realizes tension because of melancholy, depression, reliance levels go high, and general pressure coming about because of insufficiency illnesses, for example, heftiness, osteoporosis, diabetes, cardiovascular conditions among others(Chatterji et al, 2008). These conditions debilitate the wellbeing status of the old, achieve a low confidence and exhaust their underlying money related reserve funds. Getting ready for retirement and understanding individual ethnic as well as social impacts of more seasoned people is significant. Groundwork for retirement is significant as it empowers people to first, make an individual arrangement on the way of life they need to work on during retirement. Furthermore, retirement arranging gives an open door for people to make enough investment funds to provide food for their ways of life at mature age. Further, retirement arranging guarantees that people can't experience the ill effects of neediness and low confidence at mature age presumably because of absence of family support (Chatterji et al, 2008). It is imperative to comprehend the ethnic as well as social impacts of the more seasoned individual for medicinal services aides, the network and the relatives so as to treat them as needs be. Culture and ethnicity characterize the conduct and inclinations of a senior individual. It is therefore imperative to give quality human services benefits a nd develop mentalities that are adequate to these specific older folks. There are a few social effects of maturing on the old brought about by changing mentalities to maturing. One of the effects of maturing is ignoring of the elderly individuals and consequently making them to act naturally needy. This inevitably causes the matured to feel unaccepted in the public eye and in their families. Furthermore, harsh practices are coordinated to the older because of an absence of instruction on their necessities, and the current misguided judgments in regards to the matured in the public arena (Standard Poors, 2010). Thirdly, mentalities that achieve abuse of the older by affronting them sway their confidence contrarily. Maturing further restrains the degree to which the issues of older folks are perceived and overseen by the medicinal services suppliers. This is on the grounds that the older folks think that its hard to get to the offices for suitable human services. Medicinal services collaborators assume significant jobs in advancing uplifting mentalities towards more seasoned individual, and towards maturing as a procedure. In the first place, social insurance aides need to distinguish and afterward take out any close to home negative mentalities to maturing through understanding maturing real factors and perceiving normal confusions by reaching with the matured, their families and the network (Abegunde et al, 2007). Besides, medicinal services partners should help spread precise data with respect to the necessary needs and the qualities of the matured in the media. Thirdly, medical caretakers working with older folks need to go about as the significant good examples to other staff and as supporters for the privileges of the old. Fourthly, there is have to give counsel to relatives through training and the older folks on maturing as a procedure and any related handicaps (DHSSPS 2010). Medical caretakers can likewise illuminate families on the should be engaged with all parts of the older lives. Further, medical attendants must teach staff individuals in nursing homes o basic changes identified with the old, misinterpretations and the real factors of maturing. Legal and intentional offices assume significant jobs in improving the personal satisfaction for the old. Initially, the give financing to the foundation of nursing homes for the old both in the network and in focal focuses. Accordingly, even destitute seniors can get to appropriate medicinal services. The offices give wholesome requirements and recreational offices for the old in these foundations and in regions to energize physical exercise. Recovery of the intellectually sick older people is additionally encouraged alongside family trainings on the consideration for the old people. Legal and deliberate organizations likewise stage battles advancing inspirational perspectives towards the matured in the general public (DHSSPS 2010). Further, these organizations give chances to the old to give their administrations remembering humanitarian effort for request to feel acknowledged and required. Working in an office that underscores and practices quality guaranteed care assumes a significant job in building up the essential comprehension of best practice for medicinal services professionals. To start with, human services suppliers figure out how to join the most recent important as well as supportive nursing intercessions to be utilized in taking care of or enhancing medical issues (Nelson, 2010). Also, people comprehend the need to depend on research to interpret the gained inquire about based skill into the genuine nursing practice. Further, people can see best practice through mentorship and gaining from good example staff individuals, just when working in these characteristics guaranteed care settings. It is imperative to advance the personal satisfaction among the more seasoned individuals in various human services settings in light of various reasons. In the first place, more established individuals should have various human services offices to browse as far as their own accommodation. As indicated by look into distributed by Age Concern Help the Aged NI (2009), lion's share of more seasoned people favors locally established consideration, with the end goal for them to connect intimately with their relatives. Another motivation to utilize distinctive social insurance settings empowers people to pick offices that have assets that coordinate their wellbeing conditions. While locally established consideration could be essential, more established people might be compelled to be situated in medical clinics for closer wellbeing checking and treatment. Further by utilizing distinctive medicinal services setting for the old, the network, staff and families are sharpened to create uplifti ng mentalities towards maturing and the matured in the public eye. There are various ways that human services collaborators can advance the personal satisfaction to more established people. To begin with, there is have to advance uplifting mentalities inside the network, the families and the medicinal services staff towards the older (Abegunde et al, 2007). Also, one needs to urge help them to perform standard physical activities to remain fit. Another significant job ought to be centered around treating of melancholy among the matured through various important treatments. Older folks can likewise be grasped by effectively captivating them in network administration exercises like chipping in, to feel required, aside from helping them to be intellectually dynamic use (Christensen et al, 2009). The later can include the arrangement of crossword puzzles, composing challenges, cerebrum games among others. Further, arrangement of appropriate eating routine among other dietary needs is significant in keeping up their great wellbeing. There are distinctive consideration settings for the more established people comprising of pertinent specific human services groups. These settings incorporate emergency clinics, nursing homes especially for the older and locally situated setting (Age Concern Help the Aged NI, 2009). Clinics have extraordinary gerontology segments where the older are dealt with. Among the staff individuals incorporate enrolled medical attendants, specific specialists, clinical therapists/instructors, physiotherapists among others. Nursing homes for the old can likewise have Registered medical attendants, physiotherapists and various normally visiting specialists separated from mental guides (DHSSPS 2010). Locally situated consideration for the older can contain

Friday, August 21, 2020

A Sartrean Life

Sartre holds that â€Å"existence goes before quintessence. † An individual is just what the person in question wills to be. Sartre accepts that we are characterized by what we do. We are what we decide to do. Existentialism isn't a simple idea to clarify, and Sartre concurred. He summarized existentialism as presence goes before pith. What does that truly mean? Sartre clarified it utilizing the relationship of the paper shaper. He said that a craftsman whose motivation originated from an idea made the paper shaper. The craftsman alluded to the idea of what a paper shaper was and made it with a known strategy for creation (some portion of the idea of the shaper) with a daily practice. The paper shaper was delivered a specific path making on certain utilization for it. Subsequently, the embodiment (the pre-creation purpose and strategy for creation) preceded the real presence of the paper shaper, its goal and plan for creation was at that point decided. Existentialism is something contrary to this. In the event that it were existentialism, the shaper would have been made indiscriminately secretly the expectation of it until the craftsman decided a goal for the shaper after its creation. Following this line of thought, I end up in a circumstance where there would be no gloom at all since all the expectation lies in ones self. I characterize myself and my motivation in my life and I at that point assume liability for my decision by experienced my self-decided reason. . The incomparable goodness of existentialism is extreme decision. This can possibly have been gotten in the event that I am consistent with myself. I likewise need to assume liability for my own activities since I pick my own activities and should live with the results. I can pick what I become and need to live with it, yet I can transform it to make a superior fit on the off chance that I figured my decision wasn't absolutely right. In spite of the fact that Sartre’s theory has numerous preferences and it constructs itself on the conviction that we make our own decisions and we are liable for ourselves. I accept that numerous individuals won't take the test or pull out in dread of the obligation. This happens in light of the fact that it is highly unlikely for the individuals to know without a doubt that the decision they make as their meaning of themselves is right. This makes a dread in numerous individuals, a dread of being off-base and a dread that being off-base could prompt their end. Sartre conceded there was a lot of anguish in taking the existential test in light of the fact that there was no chance to get of realizing one was correct. Sartre's recommendation to the cautious was to be human, stick to ones self, and simply trust in the best. This was where existentialism approached the slender line between theory in religion on the grounds that to take this test, individuals needed to have a confidence in themselves so as to stay with their decisions. Existentialism got a lot of analysis since it was basically skeptical, yet in addition in view of the ethics it made. All things considered, the ethics were not made by existentialism, however by existentialists. They made their own ethics and qualities to follow picking their own motivations throughout everyday life. The importance of their lives straightforwardly resembled the qualities picked, in truth Sartre imagined that the qualities picked is the thing that ones significance of life depended on. This thought was emphatically condemned by numerous individuals since they expected this could make rebellion. On the off chance that everybody made their own qualities, there would be no set laws wherein to comply. Sartre expressed that ones soul would have the option to decide among good and bad; and that one could tell if their decision of activity served a shamefulness to someone else. Many were extremely distrustful of this, be that as it may; expecting that, for instance, pulling out of an understanding was satisfactory to a few, yet would not be worthy to other people. Taking everything into account, regardless of the huge measure of analysis, Sartre was generally followed and viewed exceptionally by many. He could bolster his thoughts with reason and rationale. These thoughts spoke to a lot of individuals due to the conditions they were in. The planning of Sartre was a piece of what made such an enormous after. From the beginning of time, change and the accompanying of new and some of the time radical thoughts came directly after a huge catastrophe wherein individuals were left in despair searching for trust. On the off chance that there is one thing to recall about existentialism it is that presence goes before pith. On the off chance that one is an existentialist or not: one escapes life what one places in; the importance of our lives comes not from what occurs in our lives, yet what we do in them; and all of us are entertainers on the phase of life. All things considered, Sartre said all that needed to be said when he remarked, â€Å"Man is enveloped by his own reality and there is no exit. â€Å"

Sunday, August 2, 2020

Important Warnings for Clozaril (Clozapine)

Important Warnings for Clozaril (Clozapine) Bipolar Disorder Treatment Medications Print Black Box Warnings for the Antipsychotic Clozaril By Marcia Purse Marcia Purse is a mental health writer and bipolar disorder advocate who brings strong research skills and personal experiences to her writing. Learn about our editorial policy Marcia Purse Medically reviewed by Medically reviewed by Daniel B. Block, MD on January 29, 2020 twitter linkedin Daniel B. Block, MD, is an award-winning, board-certified psychiatrist who operates a private practice in Pennsylvania. Learn about our Medical Review Board Daniel B. Block, MD on January 29, 2020 Hero Images/Getty Images More in Bipolar Disorder Treatment Medications Symptoms Diagnosis Clozaril (clozapine) is an antipsychotic medication that has been approved for use in treatment-resistant schizophrenia and for reducing the risk of recurrent suicidal behavior in patients with schizophrenia or schizoaffective disorder who are judged to be at chronic risk for re-experiencing suicidal behavior, based on history and recent clinical state. Important Warnings for Clozaril (Clozapine) Clozaril carries five serious warnings, called black box warnings, about possible severe side effects and drug interactions. Because of these warnings, Clozaril can only be prescribed through a special program that restricts distribution called the Clozapine Risk Evaluation and Mitigation Strategies (REMS) Program. Both your doctor and your pharmacist have to be registered with this program that the manufacturers created in order to prescribe and dispense your Clozaril. The REMS program ensures monitoring of WBC count and ANC according to the schedule described below prior to delivery of the next supply of medication. Be Aware of Black Box Warnings on Your Medications Agranulocytosis Agranulocytosis is an abnormally low white blood cell count. Since white blood cells are necessary to fight diseases, this is a potentially fatal side effect.   Fewer than 1% of patients taking Clozaril may develop agranulocytosis, a potentially life-threatening adverse event. If you are being treated with clozapine, you must have a baseline white blood cell (WBC) count and absolute neutrophil count (ANC) before you can start Clozaril, as well as regular WBC counts and ANCs during treatment and for at least 4 weeks after discontinuation of treatment. Risk of Seizures Seizures have been associated with the use of clozapine. Dose appears to be an important predictor of seizures, with a greater likelihood at higher clozapine doses. Caution should be used when administering clozapine to patients having a history of seizures or other predisposing factors. Patients should be advised not to engage in any activity where sudden loss of consciousness could cause serious risk to themselves or others. Seizure Symptoms, Types, and Causes Myocarditis and Cardiomyopathy Myocarditis is inflammation of heart muscle and cardiomyopathy is an enlarged heart. If you have shortness of breath, fever, extreme tiredness or chest pain while taking Clozaril, be sure to contact your doctor right away. What It Means If Your Heart Muscle Is Inflammed Other Serious Cardiovascular and Respiratory Effects Orthostatic hypotension is a large, sudden decrease in blood pressure upon standing that makes you feel lightheaded or dizzy. Syncope means fainting. Orthostatic hypotension, with or without syncope, can occur with clozapine treatment, especially when you first start taking it or your dose is changed. Rarely, this can be profound and be accompanied by respiratory and/or cardiac arrest.   If you have severe diarrhea or vomiting or other signs of dehydration, be sure to tell your doctor. Also, if you accidentally skip two or more doses of Clozaril, talk to your doctor before taking your next dose as you may need to take a lower dose for a time. Increased Mortality in Elderly Patients With Dementia Elderly patients with dementia-related psychosis treated with atypical antipsychotic drugs are at an increased risk of death compared to placebo. In one study, although the causes of death were varied, most of the deaths appeared to be either cardiovascular, meaning they were related to heart failure or sudden death, or infectious in nature. Clozaril is not approved for the treatment of patients with dementia-related psychosis.

Sunday, June 28, 2020

Disasters Analysis Discuss Potential Magnitude of Hazards - 550 Words

Disasters Vulnerability Analysis: Discuss Potential Magnitude of Hazards (Essay Sample) Content: Disasters Vulnerability AnalysisInstitutionNameOne type of disaster that may occur is that of tornadoes which are powerful and destructive weather conditions. Tornado is a violently column rotating air column that extends from the base of a thunderstom to the ground. However, their intensity varies according to the climate condition. According to the history of Anytown, it receives tornadoes during summers and it is located I humid subtropical climate zone. Woodland areas sometimes experience wildfire which is a threat to the human lives as well as wildlife (Jeffrey, 2007). Fires can be devastating to properties, homes, community and range land. According to National Fire Protection Association, about 370,000 homes in United States are destroyed by fire every year which cause deaths (Schneider, 2012). Another hazard that can occur is flooding since Anytown is located in humid subtropical climate zone. Flooding may occur especially in low lying land and along the rive r. Floods can affect a lot of homes especially those in flat and low lying land.The possibility of occurrence of floods is low especially as most of the homes are not located in low lying land. In order to prepare for such a disaster, the town is expected to contrast dykes along the river as this is the area which is prone to flooding (Jeffrey, 2007). It is however unlikely to occur as the area is not located near a major water body and it is located on highlands. This means that the amount of runoff water is little to cause major floods which would destroy buildings.However, possibility of occurrence of tornadoes is high as the area is reported to be experiencing such weather conditions. In U.S tornadoes occur in months of April, May and June and occur in areas experiencing humid and warm air just like the weather conditions of Anytown. Areas with tall buildings are more likely to be highly affected and they would cause more destruction in these areas in terms of destruction of pr operty and loss of human lives (Schneider, 2012). However, the likelihood of a tornado hitting the area with large building is small but it can hit other areas with residential buildings. Tornados warning are issued by weather services warning against extreme weathers and tornadoes.Possibility of wildfire occurrence is medium and therefore frequency of occurrence can be said to be possible. The potential magnitude of occurrence of wildfire is critical as they are caused by human activities such as smoking and throwing fire to areas under grass (Cutter, 2001). Wildfires can affect homes located near forests while areas with tall building such as downtown can experience fires as well. Wildfires can be experienced during summers when the region is experiencing high temperatures and the grass or trees are dry (Cutter, 2001).Threat Profile Worksheet Threat: Earth quakes Potential Consequences * Catastrophic (Mass fatalities/casualties, loss of governance and essential services, widesprea d damage) * Severe (Numerous fatalities/casualties, loss of essential services, and widespread damage) * Moderate (Limited number of fatalities/casualties and damage to property) * Minor (Little or no injuries and isolated damage)Severe Probability of o...

Saturday, May 23, 2020

Custom Component Development in Delphi

Components are essential elements of the Delphi environment. One of the most important features of Delphi is that we can use Delphi to create our own components. We can derive a new component from any existing component, but the following are the most common ways to create components: modifying existing controls, creating windowed controls, creating graphic controls, subclassing Windows controls and creating nonvisual components. Visual or not, with or without property editor, from scratch...you name it. Developing Delphi components isnt a simple task, it involves quite a bit of knowledge of the VCL. However, developing custom components is not an impossible task; writing components is just pure programming. Articles, Papers, Tutorials What follows is a list of articles that deal with custom component development in Delphi. Accessing protected members of a componentMany Delphi components have useful properties and methods that are marked invisible (protected) to a Delphi developer. In this article, you will find the workaround to this problem - thus enabling you to access a DBGrids RowHeights property, for example.Creating Custom Delphi Components - Inside and OutThis tutorial will explain component writing to you, which should result in more code reuse. It will go over properties, events, and methods, and will also explain how to install components. The final part of this tutorial is about Object-Oriented design.Creating Custom Delphi Components, Part IThis first part demonstrates some of the best approaches to building components, and at the same time provides tips on deciding on the best base class to inherit from, using virtual declarations, the complexities of overriding, and so on.Creating Custom Delphi Components, Part IIQuite often it is necessary to write components that perform more advanced f unctions. These components often need to either reference other components, have custom property data formats, or have a property that owns a list of values rather than a single value. We will explore various examples covering these very subjects, starting with the most simple.Creating Custom Delphi Components, Part IIIThis article is the final part of a three part article on components. Part one covered the basic creating of components, part two covered how to write advanced properties, how to write custom streaming for those properties and sub-properties. This final part will cover property/component editors, how to write dedicated editors for your component/property, and how to write hidden components. More Resources First, if you want more, consider buying a book on Developing custom components.Second, why not try locating an existing (with source perhaps) component you are looking for.Third, when you are 100% sure there is no such question on custom component development you cant answer...there will be something that you dont know. Everything you have to do is to ask a question on the Delphi Programming Forum and wait for answers. Articles, papers, tutorialsHere is a list of articles that deal with custom component development in Delphi. VCL Component Messages [RTF]Component Messages (CM_) are generated only by the VCL and are not reflected Windows Messages (WM_), as one may assume. In spite of that Component Notifications (CN_) are reflected Windows Messages. The idea behind it is, that Windows often sends messages to a parent window of a control instead of the control itself. The VCL simply converts (reflects) these messages to Component Notifications and then sends it to the control, for which the message originally was meant. Delphi Component Building.In this article, read about every aspect of Delphi Component building. Design a TTicTacToe component and learn about: how to build our own components for Delphi, how to add properties, methods and custom events to them, how to wrap them around DLLs, how to install them, how to design a palette bitmap and write on-line help to support the component user. Building SuperComponents in Delphi [download]SuperComponents, also known as aggregate or compound components, are collections of existing sub-components and their relationships combined into a single component. The collections are typically arranged inside a container parent component that manages the visual layout of the sub-components.

Tuesday, May 19, 2020

Dub Poetry in and from Jamaica - 9895 Words

Table of Contents 1 Introduction 2 2 History and Development of Dub Poetry 3 2.1 The Development of Jamaican Creole – Short Overview 3 2.2 The Oral Tradition 4 2.3 From the B-side of a Record via â€Å"Toasting† to Dub Poetry 6 3 The Correlation of the Rastafarians, Reggae and Dub 9 3.1 The Rastafarians 9 3.2 The Peculiarity of Dub 10 3.3 Artists and Scenes 12 3.3.1 The Jamaican Scene 12 3.3.2 The British Scene 13 3.3.3 The Canadian Scene 14 4. Structural Characteristics of Dub Poetry 15 4.1 Patois – the Language 15 4.2 Rhythm 15 4.3 Performance 17 5 Linguistic Analysis of Dub Poetry Lyrics and Performance 18 5.1 Linton Kwesi Johnson 18 5.2 Wat about di Workin Claas? 19 5.3 Tings an Times – Performance Aspects in Comparison 21 6 Reflection 23†¦show more content†¦It is closely connected to the period of massive slave importation and the miserable circumstances of the slaves during the period of British colonisation in the West Indies. The developmental history of language in British colonies like Canada or Australia is extremely different from that of the West Indies. The settlers predominantly from the British Isles spoke English and automatically passed the language on to their descendants and to others through close contact, whereas in the West Indies slaves from divergent African regions were imported to work on sugar plantations, with most of them stemming from different linguistic backgrounds. People were hardly able to communicate among each other and therefore it came to â€Å"a restructuring of English that resulted in Creole, a distinct language system with words derived from English but with phonology, semantics and morphosyntax influenced by African languages and other forces† ( Holm 1994: 328). The slaves were hardly in contact with the white English speaking population but had to communicate with the other slaves and the white overseers. The Creole phoneme system is modified to accommodate the West African languages and the lexicon contains many English stemming wordsShow MoreRelatedOral Traditions or Spoken Word in the Caribbean1557 Words   |  7 Pagesessential in promoting effective communication, family life, togetherness of the community and conflict resolution. The telling of stories, playing of games, poetry, oratory and debating were critical for disseminating information, passing on traditions and educating a people about themselves. The telling of stories, playing of games, poetry, performance and oratory are still a large aspect of who we are. Even regionally too, we see these traditions manifested in the richness of the nation languagesRead MoreEssay about Jamaican Patois4705 Words   |  19 Pagesp . I 1) Creole languages are actually not unique to Jamaica, they are found on every continent although their speakers often do not realize what they are. The rest of the terms refer strictly to Jamaican Creole. Creoles are languages that usually form as the result of some human upheaval which makes it impossible for people to use their own languages to communicate. What people often refer to as the bad or broken-English of Jamaica are actually local Creoles that usually come about throughRead MoreHip Hop: The Method of Expression1099 Words   |  5 PagesFrom the impoverished section of Bronx, New York arose a youth culture that spread throughout the community like wild fire. Within the gang-ridden, drug-infested streets, a depravation of creativity forced underprivileged African American youths onto the streets in search of an output for their imagination. It was within these streets that hip-hop appeared as the product of independence, self-realization, creativity, and pride. Hip-hop began between the transformations from the late 1960’s toRead MoreThe Youth Oriented Hip Hop Movement1498 Words   |  6 Pagesgang activity was eventually replaced by local dance and music crews such as Zulu Nation, which was led by one of the early fathers of hip-hop, Afrika Bamaataa. An immigrant from Jamaica, DJ Kool Herc was one of the first to bring dub music to New York City in the late 1960s. According to Toop (1991) and George (1998), â€Å"dub music evolved into different genres including reggae and dancehall and would eventually evolve into hip-hop† (referenced by Persaud, 2011, p. 5). Soon, by the late 1970s, hip-hopRead MoreWhat Is The Types Of Music?1587 Words   |  7 Pages What is the types of music? Music became an important thing since i was really young.It grew up with me together and it brings me a lot of things that other things can’t give me.Now,let me tell you all about what i learned from music,and my feeling with music.I found there are many different types of music.And every type of music brings listener different feelings.Types makes music totally different. If i am a narrator,then music is like a main character in my life.ActuallyRead More Jamaican Patois and the Power of Language in Reggae Music Essay4989 Words   |  20 PagesMost Creole languages are based on one language. In Jamaica the African slaves were thrown into a situation where the only common means of communication was English, or at least broken English, therefor Jamaican Creole has a majority of its roots in English (Sebba 1, 1996). Essential words which people could not find an English name for, such as people, things (like plants and animals) and activities (especially religious ones) were taken from a variety of West African languages. As a resultRead MoreHip Hop And Its Influence On The Culture Essay2067 Words   |  9 Pageswithin the framework of equal temperament) with those of African origin which employed the natural harmonic series and blue notes† (Wikipedia, 2016). Also, explain the exceptions are hip hop, house, and techno, which were formed in the late 20th century from earlier forms of African-American music such as funk and soul. All modern-day music is heavily influenced by previous and present African-American music genres. My purpose is to give you a clear understanding on how Hip-Hop music not only changed theRead MoreThe Golden Era of East Coast Hip-Hop2032 Words   |  9 PagesThe Golden era of east coast hip-hop This piece will demonstrate an understanding of the golden era of East coast hip-hop, from 1986 to 1993, focusing and analysing the historical roots, influences and inspirational individuals, giving reference to musical examples that shaped East coast hip-hop. Attention will also be centred on the legacy left, concentrating on the music that was influenced as well as the resulting change in fashion and political views. Historical roots influence TheRead MoreHip Hop : A Whole New View2776 Words   |  12 Pagesgeneration that are new and have never been seen before. Social media is a huge one. However, there is a specific aspect of our generation that started from the generation before us. This is a huge part of the culture of young adults today and means a lot to many teens. That part of the culture is music. Music has this weird way of bringing together people from all walks of life. Music sensation, Rihanna, has her own song titled â€Å"Please Don’t Stop the Music†, which talks about how music gets people grooving

Monday, May 11, 2020

William Cullen Bryant And Transcendentalism - 833 Words

â€Å"William Cullen Bryant is the author of Thanatopsis. Bryant was born in Cumington, Massachusetts, and began writing poetry before he was nine years old. Bryant’s family is Puritan family, when he was a child, he was often ill, and his father asked him to walk in the forest to strengthen his constitution, which gave him a keen interest in nature. Bryants position combines the impulses of the British romantic school and his own New England conservatism. His life gradually moved away from the Calvinism of religion, the political transition from federalism to unification and Jacksons democratic attitudes. He thought poetry was an art of association, it inspires readers imagination with symbolism rather than direct imitation of life, and†¦show more content†¦The transcendentalists believed strongly in the power of the individual. Their beliefs are closely linked to romanticism, but they differ from attempts to embrace or at least not oppose scientific empiricism. The transcendentalists wanted to place their religion and philosophy in their principles rather than on, or falsified, physical experiences, but from the inner spiritual or spiritual nature of the human being. The transcendentalists argued that society and its institutions, particularly organized religions and political parties, corrupt the purity of the individual. They believe that people are at their best when it comes to true self-reliance and independence. Before William Cullen Bryant was 17 years old, he wrote a poem called â€Å"Thanatopsis†. This poem is about death and nature how to related to each other’s. Transcendentalists is how the God, nature and men connect to each other, and in Thanatopsis, Bryant combined with death and nature, nature is our final destination of mankind, and human death will enter into the world where God is, he compared nature to God. Bryant not afraid of death, he thinks when he dead, he can go back to â€Å"her†, the nature. He feels death like a long sleep, we shouldn’t afraid of death, we can’t be treated death as pain. â€Å"but, sustained and soothed. By an unfaltering trust, approach thy grave† (Thanatopsis by William Cullen Bryant ) â€Å" When thoughts Of the lastShow MoreRelatedThe Fall Of The House Of Usher1651 Words   |  7 PagesMason Eggers Mrs. Szwajkowski Junior English 200 24 March 2016 Romanticism/Transcendentalism Essay Edgar Allen Poe’s â€Å"The Fall of the House of Usher,† Nathaniel Hawthorne’s â€Å"The Minister’s Black Veil,† and William Cullen Bryant’s â€Å"Thanatopsis† illustrate several Romantic and Transcendentalist (and anti-Transcendentalist) traits. All of these authors are regarded as very important and influential Romantic writers. Their works are renowned all across the entire world. â€Å"The Fall of the House of Usher†Read More`` Contemplations `` By Anne Bradstreet Essay1462 Words   |  6 Pagesnational church†¦ purging it of everything that harked back to Rome, especially the hierarchy of the Clergy and all the traditional Catholic rituals† (â€Å"John Winthrop† 165). Much like the Puritan period, the later nineteenth-century movement of Transcendentalism also took place in New England. However, there were some stark differences between the two. For instance, although a â€Å"religious quest†, Transcendentalists were not entirely motivated by religion. While the Puritans were devoted to reform andRead MoreDeath in Thanatopsis by William Cullen Bryant Essay447 Words   |  2 PagesDeath in Thanatopsis by William Cullen Bryant When people ponder death they wonder about the unknown with trepidation. As a young man, William Cullen Bryant wrote the Thanatopsis. His thoughts progress from the fear of death to the acceptance of the event. People should not fear death because everyone dies and becomes a part of nature. A person should live life without fearing death and think of death as a pleasant rest. In the poem Bryant says, When thoughts/Of the last bitter hourRead MoreJohn Smith And Walt Whitman Essay1248 Words   |  5 Pagesinto the realist movement and nature was viewed not as an extension of god, but as a way to learn about ourselves and the world. opposition to romanticism. Three writers between these two time periods, Jonathan Edwards, Benjamin Franklin and William Cullen Bryant each have a different worldview based on their background and provide a transition between the Puritan and Realism movements. John Smith came to the new world with the Virginia Company in order to colonize the land and to start a new, economicallyRead MoreThe Language Of Nature In Thanatopsis By William Cullen Bryant712 Words   |  3 PagesIn his literary piece, â€Å"Thanatopsis†, William Cullen Bryant introduces his logic on why we should see the favorable circumstances within nature. He speculates his reasoning that there is an innate capacity to brighten up all of the sinister thoughts that frequently occur in our brain and consciousness. He elaborates that we shouldn’t take the time to endure the way of perturbing ourselves in relation to death, because death is unavoidable and imminent. Alternatively, we ought to take that time toRead MoreEarly American Literature Essay1511 Words   |  7 Pagesother writers to come. Around the same time as Irvings Rip Van Winkle, William Cullen Bryants Thanatopsis displayed a pantheistic view of nature as imbued by God (7th ed, p, 476). Bryant, jus t as Irving, saw the American landscape as an all-inspiring motivation for many of his stories. Bryants poetry focused on nature as a metaphor for truth established a central pattern in the American literary tradition (William). As America continued to grow and developed so did its writers. A majorRead MoreThe Adventures Of Huckleberry Finn By Mark Twain1545 Words   |  7 Pagessociety believes is right. In Emerson’s short essay, â€Å"Nature†, Emerson describes nature as a place in which it provides protection from all calamities and disgraces. While in nature, he’s able to become relaxed and peaceful. In William Cullen Bryant’s poem, â€Å"Thanatopsis,† Bryant writes that although everyone will eventually die, death shouldn’t be feared, but instead embraced. While nature does bring death, it also provides care and a sanctuary, which clears our dark thoughts away. Although nature canRead MoreThe Spirit And Beauty Of Nature, And The Power Of The Natural World1172 Words   |  5 PagesThe Romantic worldview emphasized the glory and beauty of nature, and the power of the natural world. A branch within Romanticism was Transcendentalism and its followers believed that â€Å"unifying principles could be found in the natural world, which became a sacred space that pointed to the immanent presence of the divine† (Sayre 877). Aspects found in nature have the ability to cause an individual to have a revelation as to why their life is unpleasant and allows them to find their purpose in lifeRead MoreBrief Survey of American Literature3339 Words   |  14 PagesSettlers’ Writings Highly religious and pragmatic - John Smith, founder of Jamestown, Virginia; Pocahontas - John Winthrop, â€Å"A Model of Christian Charity†: â€Å"†¦ We shall be as a city upon a hill. The eyes of all people are upon us†¦Ã¢â‚¬  - William Bradford, Of Plymouth Plantation (1630-50, pub. 1856) - Anne Bradstreet (1612-1672), The Tenth Muse (1650), the first volume of poems published by a resident of the New World - Edward Taylor (1642- 1729), Preparatory Meditations (1682-1725Read More Puritanism: The People, Religion, and Poetry Essay4374 Words   |  18 Pagescommunicate something and rightly be interpreted by people. Though particular poets had different reasons for why it could be done, they all continued to operate as if it could be done. Without the theism of Puritanism, reading the book of nature became William Cullen Bryants Thanatopsis presents a personified nature to which everything and everyone is connected and belongs. In life, people are nourished by the earth and at death, people become part of it. He and other Fireside poets had a high view of nature

Wednesday, May 6, 2020

Risk Management For Healthcare Organizations - 1442 Words

Introduction Risk management refers to the process of forecasting, estimating and evaluating the possible risks that are likely to befall an organization in the normal process of conducting its activities. It includes the identification of measures, methods, and procedures to mitigate them. Healthcare risk management is the process of estimating and forecasting the potential risks relating to patient safety, staff, adherence to federal regulations, prevention of medical errors and prevention of financial loss of the entire healthcare organization and the steps necessary to mitigate them. Healthcare organizations use service-based ERM. Potential Risks in Healthcare Organization Risk management in healthcare organizations revolves around patient safety, adherence to industry and federal regulations for the medical industry, prevention of medical errors and prevention of financial loss. Potential risk areas therefore include: Patient Safety: patients are entitled to quality services from the hospitals and other healthcare units. However, lack of expertise and qualifications among medical staff may jeopardize patients safety. It can lead the poor administration of medical services, which may bring other complicated health issues to the patients. Patient safety is an area of risk in healthcare organizations where the medical staff has no minimum qualifications required for the profession or in situations where doctors and physicians administer medication to patientsShow MoreRelatedRisk Management Plan For Accreditation Of Healthcare Organizations1884 Words   |  8 PagesAccreditation of Healthcare Organizations (JCAHO), risk management is defined as â€Å"c linical and administrative activities undertaken to identify, evaluate, and reduce the risk of injury to patients, staff, and visitors, and the risk of loss to the organization itself† (The Joint Commission on Accreditation of Healthcare Organizations, 2005). Outlined below is a risk management plan which consists of goals, responsibilities, roles, definitions, emergency plans, contingency plans, departmental organization, andRead MoreRisk Management Plays a Vital Role in Healthcare Organizations606 Words   |  3 Pages Risk managers are a vital lifeline in the healthcare organization. If this organization had an active risk manager in place, many of the events leading up to the infant losing its life could have been prevented. There are many steps that a risk manager must take once a risk is identified, this paper will walk through the steps that are required after the risk happened. A risk manager plays an important role with the events in this infant case study. Risk managers hold a wide varietyRead MoreHealthcare Risk Management ( Hrm )1216 Words   |  5 Pages Healthcare risk management ( HRM) began in The late 1970s, when hospitals are facing a malpractice crisis (Kavaler Alexander, 2014). According to Kavaler and Alexander (2014), it is estimated more than 140,000 Americans die from medical errors and the cost ranges between $17 billion and $29 billion each year in the United States (Kavaler Alexander, 2014). In this essay, the student will explain a healthcare risk management program, evaluate the program for compliance with the American SocietyRead MoreRisk Management Program For New Employees1144 Words   |  5 PagesThe risk management program in any business, especially in a health care organization is an integral part of its day to day operation. The purpose of the risk management department is summed up by Kavaler Alexander (2014), â€Å"†¦a program designed to reduce the incidence of preventable accidents and injuries to minimize the financial loss to the institution should any accident or injury occur† (p. 5). P rotecting employees, patients, vendors and visitors is an ongoing process and one that needs toRead MoreMedical Necessity Should Be Reduced By Eliminating Unnecessary Care Being Administered Essay1604 Words   |  7 PagesPage 1 CCHC has determined that the current costs that impact the healthcare organizations today can be reduced by eliminating unnecessary care being administered. Unnecessary care accounts for at least from 1/3 to  ½ of healthcare costs, which in turn attributes to lost employee productivity. It has been determined that the administration of elective procedures is unnecessary. Focus should be placed on a patient’s immediate condition, and procedures should be performed to bring this condition toRead MoreComponents Of A Risk Management Program1170 Words   |  5 PagesEvery healthcare organization, no matter how small or specialized, should be aware of its risk situation and take appropriate measures to protect itself against clinical, financial and operational exposures. Risk management is the process of minimizing risk to an organization by developing systems to identify and analyze potential hazards to prevent accidents, injuries, and other adverse occurrences, and by attemptin g to handle events and incidents which do occur in such a manner that their effectRead MoreThe Potential Of Risk Within Healthcare1312 Words   |  6 Pagespotential of risk within healthcare is a high factor concern when dealing with hundreds of patients, staff, and the organization as a whole. Defining what risk is and the level of importance it represents is the first objectives taken on when risk is presumed. Risk within a healthcare facility is when anybody inside the organization or the organization itself is somehow put in harm s way due to ill practice or internal error residing in the hospital. Proper risk Management defined in healthcare means patientRead MoreWorking Capital Management in Healthcare Essay1514 Words   |  7 PagesWorking Capital Management in Healthcare Houma Guy. HCS 579 Health Care Finance September 24, 2005 Working Capital Management in Healthcare Working capital is the money required to finance the day to day operations of an organization. Working capital may be required to bridge the gap between buying of stocked items to eventual payment for goods sold on account. Working capital also has to fund the gap when products are on hand but being held in stock. Products in stock are at full cost, effectivelyRead MoreElements Of A Risk Management Program1400 Words   |  6 PagesElements of a risk management program Introduction Quality and safety of care are the biggest goals of every health care organization. A risk to the patient, healthcare professional and the organization are prevalent in health care settings, which can be minimized and prevented by having well trained and educated risk management team within the organization. Risk management is the systematic effort to reduce an incidence of preventable accidents, which not only prevents the injuries and financialRead MoreAn Examination Of The Healthcare System1090 Words   |  5 Pagessecurity has become a universal concern. An examination of the healthcare system reveals that it is not exempt from the same information security challenges that other organizations face. The use of information technology in healthcare offers significant benefits, such as improved safety and healthcare quality, reduced cost of healthcare, greatly increased efficiency within healthcare operations, and better collaboration among healthcare professionals. However, as prov ider and patient data are converted

How Does Owen Convey Negative Feelings in the Send-Off Free Essays

How does Owen convey negative feelings in The Send-Off? In this poem Wilfred Owen conveys negative feelings with his clever use of language that can be interpreted in many ways. This poem actually conveys a message that war is not as glorious and honourable as it is always portrayed as. Even the title, The ‘send-off’ could mean two things. We will write a custom essay sample on How Does Owen Convey Negative Feelings in the Send-Off or any similar topic only for you Order Now Firstly, it could mean that the soldiers were being sent off to war. However, it could also mean that the soldiers were being â€Å"sent off† to their deaths. This emphasizes the fact that war actually is not what it is portrayed to be. It is not glorious and honourable to fight in war but the people and soldiers going through it suffer greatly and most do not survive. In â€Å"The Send-Off†, Owen conveys his feelings about the war and the young soldiers going off to die. You can tell he has a very pessimistic attitude to the likelihood of the soldiers surviving. You can see this from his frequent references to death, for example â€Å"Their breasts were stuck all stuck with wreath and spray. † which could refer to how the dead are garlanded with wreaths of flowers before their burial. Line six, says, â€Å"Dull porters watched them / and a casual tramp / stood staring hard. The train station porters stand back, watching and listening to the soldiers as they wait for the train with no emotion at all, it is as if it is just one of those regular things in life that one gets on with, without much interest as it is such a common event. In line 3, Owen uses the oxymoron, â€Å"grimly gay†, this give s the impression that the soldiers know what is going to happen to them and they are scared, but they put on a brave face anyway so as not to upset their families, each-other and also, if they don’t admit their fear to themselves, then maybe it will go away. Owen uses similes such as â€Å"so secretly like wrongs hushed up† show the conspiracy of the war kept from the soldiers for assurance that men would continue to join. Repetition of â€Å"a few, a few, too few† emphasises and shows the reader that many soldiers would not return from war. It continues by suggesting that the small amount of soldiers returning from war would not be greeted by celebration but by silence and still villages. The use of imagery â€Å"white flowers† shows two meanings, flowers for celebrating and white for mourning. In giving the flowers to the departing soldier, the women who thought they were supporting the soldiers were actually garlanding them for death. To conclude, the use of language; similes, repetition, imagery and so on all channel feelings of negativity within the poem. Although not directly pessimistic it is relatively easy to spot the depressing nature of the poem but nonetheless Owen displays obvious negativity towards the state of how no one showed feelings towards the soldiers fate and how it was so hushed up. How to cite How Does Owen Convey Negative Feelings in the Send-Off, Essay examples

Islam Persuasive Essay Example For Students

Islam Persuasive Essay Islam is a monotheistic faith that means submission to the will of God. The person who practices this faith is known as a Muslim. As someone who has grown up in India, which has more than 100 million more Muslims on its subcontinent alone as compared to all the Arab countries combined, I have had several interactions with Muslims, both positive and negative. However, I now realize that those interactions were limited and that there is a lot more that I did not know about Muslims from different countries, who are scattered all around the world. I am fascinated by the fact that there are around 6 million Muslims in the United States. As Muslim immigrants comprised a steadily growing group in the United States before the attacks of September 11, it was estimated that the increasing rate of their population going to make Islam the nations second largest religion by the year 2010. Hence, mental health professionals in this country are paying a lot of attention to the needs of Muslim clients based on their religious doctrines. There are five basic articles or pillars of faith in Islam. These are Ashshahadatan (testifying that there is no God save Allah and that Mohammad is the messenger of Allah), Assalah (a form of worship rites that involve specific movements and sayings, which need to be performed five times a day), Azzakah (to pay 2.5% of the wealth annually for the benefit of the needy in Muslim community), Assawm (To abstain from eating, drinking and sexual intercourse during daytime throughout the 9th Lunar month), and Al Hajj (The pilgrimage to Mecca once in life for those who are physically and financially able). Research has found that Muslim societies are collectivistic (group plays a larger role in society than the individual) in terms of family life, economic situations, the truth as determined in terms of agreement with the Koran, their religious book, and religious, and aesthetic values. Moreover, according to a fundamental doctrine in the Islamic faith, Muslims believe in fate and perceive illness as a way of atoning their sins rather than a form of punishment.. I have also discovered that I had certain preconceived notions about Muslims based on my experiences as a person from India, where Muslims are minorities just as they are in the United States. However, the majority group in India, to which I used to belong to, had hostile feelings towards Muslims. And I grew up developing feelings of prejudice and negative emotions toward the population. This project has made me develop insight into my faulty thinking and wrong assumptions enough to change my prejudiced attitudes towards Muslims and to view them as I would view any other population that is different from my own, irrespective of their race or religion. As a foreigner in this country, I also realize that acculturation is as difficult for any foreigner as it has been for me. Hence, before offering any services to a Muslim immigrant, it is essential to find out what his level of acculturation in the United States is. This can alert me as a practitioner about what cultural conflicts might interfere with otherwise ideal treatment interventions. I understand that I need to base my interpretations of my clients within their cultural context. All in all, I would not hesitate to say that this process of understanding a Muslim client has been a lot of hard work academically as well as emotionally. At the same time, as I gained increasing knowledge of Islam and its followers, I felt a sense of achievement and also a sense of unburdening myself from the prejudices that I have held since my childhood. As a psychologist, I have realized that with my past education so far, it was becoming easy to empathize with clients and the problems that they brought to therapy. But I had never viewed them as individuals with a different religion as mine at such a conscious level, to understand what practicing that religion meant to them and how it would affect their role as not only a client within the mental health settings, but also as a client of a therapist who practiced a religion very different from theirs. This reinforces the fact that the becoming of a sensitive therapist is an evolving process, and that one can never be stagnant or content with having enough education

Thursday, April 30, 2020

The Effects Of Marijuana On The Brain Essays - Cannabis Smoking

The Effects of Marijuana on the Brain Marijuana has been illegal for years because of the thought that it was a drug similar to cocaine, or heroin. Drugs such as cocaine and heroin affect the neurotransmitter dopamine. Dopamine is the neurotransmitter associated with extremely pleasurable sensations. If a drug interferes with its production and causes too much to be produced the result is extremely pleasurable and can lead to severe abuse and addiction. It has recently been proven that marijuana is not a drug that affects the production of dopamine. The average marijuana plant contains over 400 chemicals and when the plant is smoked or vaporized the heat produces many more. Receptors in the nerve cells of the brain receive these chemicals and the chemicals cause the nerve cell to change in some way. The chemical in marijuana that has the biggest impact on the brain is THC (tetrahydrocannabinol). THC receptors are abundant in the brain but they are concentrated in certain areas. One region of the brain where THC receptors are highly concentrated is the hippocampus. The hippocampus is the area of the brain that processes memory. When THC attaches to receptors in the hippocampus, it weakens short-term memory. The hippocampus also communicates with other regions of the brain that process new information into long-term memory. So under the influence of marijuana, new information may never register and be lost from memory completely. There is also a dense concentration of THC receptors in the basal ganglia and the cerebellum. Both of these areas affect movement and coordination. One area that does not contain any THC receptors is the medulla. The medulla controls many functions essential to life such as heart rate and digestion so the lack of receptors in this area has prevented any deadly overdoses of marijuana. In addition to having significant effects on the brain and impairing memory and coordination, marijuana has effects on other viscera as well. Marijuana causes the heart to beat up to forty times more per minute. This can cause heart attacks or heart failure. Approximately 1% of all heart attack victims suffer their heart attacks on the same day as using marijuana and .2% of victims say that they smoked marijuana within one hour of their attack. The effects of marijuana on the heart and other organs can be very dangerous, however this effect is highly insignificant compared to the effects on the brain. Marijuana can be very dangerous if used in excess. Though it does not cause the user to become physically dependent it can cause them to become psychologically dependent. The brain is quite possibly the most important organ in the body and the use of marijuana causes the brain to function in ways that can be dangerous to the user or to others and for this marijuana is illegal, and justly so.

Monday, April 13, 2020

What Are These Essays?

What Are These Essays?The Gre issue essay sample is a valuable resource for students who are interested in achieving higher grades. In this essay, you will be given examples of important topics to consider when writing an essay. Each issue includes high quality examples from famous literature, movies, music, and more. This is an ideal resource for college students who are interested in turning in their best work.The essays that you will be given in the Gre issue contain a number of questions that can help you determine whether you have any strengths or weaknesses in a particular topic. Some examples include the following: what makes a career choice effective and exciting? What motivates a successful person?Each topic also includes a section on successful people and what they have achieved in their student's life. If you do not know what the characteristics of successful people are, this is a good source to read up on that. The essay sample also includes an examination of individuals who helped make our world the way it is today.The Gre issue essay sample is an excellent way to put your ideas into action. It gives you a variety of essays to choose from and allows you to do more research than you would be able to do otherwise. This makes for a better and more fulfilling academic experience.Each issue also features a variety of sample essays written by authors and writers. Some examples include works by authors from the fifteenth century, twentieth century, and more recent works. The essays that you will be given in this issue include more current authors and are formatted accordingly. You will enjoy reading these samples as well as researching for yourself.Topics can vary from one issue to another. While some issues have long, general topics that cover a wide range of topics, others will focus on a specific topic. You will find that the topics given in these samples are always related to the topics you study throughout your coursework.These essays in the differen t issues contain sample essays and include different types of topics. For students who are just starting to learn how to write essays, this is an ideal resource to read through before they start writing their own. These essays in the issues contain essay samples that can help you gain insight into various essay topics.

Saturday, March 21, 2020

Free Essays on Real Property Investment

Why do people use real property investment? Investment in property is most important investment instrument in Australia, as you know the richest 200 people ¡Ã‚ ¯s wealth is based on the real property. Although property must be viewed as an illiquid investment because the transfer costs of properties are high and the selling period averages several months, according to steady profit return and low risk, many people buy in property to against currency inflation, and to compensate increasing life expense contrasted to decreasing social security after retirement. How does it work? Negative gearing Gearing basically means borrowing to invest. An investment property that's negatively geared is purchased with a loan that has an annual net rental income amount that is less than the annual interest paid on the loan, plus the deductible expenses associated with maintaining the property. You get tax benefits by being negatively geared as you are able to deduct the costs of owning an investment property from your overall income. The biggest part of this deduction is the interest portion of your mortgage, but you can also claim such expenses as property management fees, loan costs and repairs. Because negative gearing deductions offset your income, they are most beneficial to high-income earners. What this means is the more you borrow, the more interest you pay and the bigger your deduction. While everyone wants a large tax deduction, you shouldn't over commit yourself in order to get one. You still have to make the mortgage payments and those lucrative tax benefits don't arrive until the end of the financial year. In periods of low inflation, the benefits of negative gearing are usually negligible. (Case study: Mr. Bill teaches accounting in TAFE. He is interested in a 2 bedrooms unit in Parramatta, which costs $360,000. His annual salary is $50,000. He gets $376,190 mortgage at 6.29% p.a. from Wizard home loan, calculate how much money ... Free Essays on Real Property Investment Free Essays on Real Property Investment Why do people use real property investment? Investment in property is most important investment instrument in Australia, as you know the richest 200 people ¡Ã‚ ¯s wealth is based on the real property. Although property must be viewed as an illiquid investment because the transfer costs of properties are high and the selling period averages several months, according to steady profit return and low risk, many people buy in property to against currency inflation, and to compensate increasing life expense contrasted to decreasing social security after retirement. How does it work? Negative gearing Gearing basically means borrowing to invest. An investment property that's negatively geared is purchased with a loan that has an annual net rental income amount that is less than the annual interest paid on the loan, plus the deductible expenses associated with maintaining the property. You get tax benefits by being negatively geared as you are able to deduct the costs of owning an investment property from your overall income. The biggest part of this deduction is the interest portion of your mortgage, but you can also claim such expenses as property management fees, loan costs and repairs. Because negative gearing deductions offset your income, they are most beneficial to high-income earners. What this means is the more you borrow, the more interest you pay and the bigger your deduction. While everyone wants a large tax deduction, you shouldn't over commit yourself in order to get one. You still have to make the mortgage payments and those lucrative tax benefits don't arrive until the end of the financial year. In periods of low inflation, the benefits of negative gearing are usually negligible. (Case study: Mr. Bill teaches accounting in TAFE. He is interested in a 2 bedrooms unit in Parramatta, which costs $360,000. His annual salary is $50,000. He gets $376,190 mortgage at 6.29% p.a. from Wizard home loan, calculate how much money ...

Wednesday, March 4, 2020

5 part-time jobs great for college students

5Â  part-time jobs great for college students Being a college student can be rough work- on top of juggling a heavy class load with extracurricular activities and social opportunities, many students look to take on some type of part-time employment, either to help pay for school or for extra spending money. That’s a lot to handle, and it’s exactly why students should make every effort to ensure that they’re choosing the right types of jobs. An ideal part-time job allows for some level of schedule flexibility to accommodate busy lives in and out of the classroom and will not eclipse or overshadow a student’s primary goals- to get good grades and have a positive college experience.Monster recently published an article highlighting some of the best part-time jobs for college students. If you’re a student on the hunt for a part-time job, consider the following five possibilities.1. BabysitterTaking care of children has long been a tried and true employment opportunity for students. Why? Because stu dents typically have the energy and enthusiasm to keep up with young children. Babysitting is typically the sort of work students can do around their class schedules- night and weekend work is common. It also tends to pay relatively well and you can pretty much set your own work hours and availability.2. BaristaCollege students have long-since discovered the power of coffee to get through a long and busy day, and many students have also discovered that making and serving coffee can be an excellent way to earn some extra cash. Not only are there coffee shops practically everywhere (especially around college campuses across the country), they also typically offer work shift opportunities around classes and can be fun and social environments- not a bad way to earn a paycheck.3. DriverIf you have a car and a little extra time on your hands, becoming a driver might be a great choice for part-time work. For the most part you’ll get to be your own boss, set your own hours, and work from the comfort of your own car. Work when you’re available, look forward to some extra tips from grateful passengers, and have plenty of time to handle the rest of your busy life.4. IT support specialistThese days, the average college student was practically raised on technology and has solid tech skills that they can put to good use. If you often find yourself helping friends and family with their tech-related issues, why not get paid for it? You can either employ yourself or find a job on campus as an IT support specialist and earn good money doing something that you’re naturally good at.5. Retail associateMost of us at one time or another held at least one job in retail- and for good reason. These jobs are often easy to find and are flexible, relatively low-stress ways to earn some extra money. If this sounds right up your alley, head out to some stores in your area and see if they’re hiring.There you have it- if you’re a college student on the hunt for a part-time job, one of these five options might be just the right move for you. Happy hunting!

Monday, February 17, 2020

Case study of an organization that has experienced or is experiencing Essay

Case study of an organization that has experienced or is experiencing an ethical dilemma - Essay Example And despite the corporation’s attempts to clean up its image in the global marketplace, mostly by launching Fair-trade products in various developed countries, recently Nestlà ©Ã¢â‚¬â„¢s reputation was damaged even more by the same morally reprehensible tactics it employed decades ago (Merrett, 2007). Our case study, however, will focus expressly on the controversy which Nestlà © Corporation brought upon itself decades ago in the 1970s by utilizing questionable marketing practices in selling its products to vulnerable mothers in developing nations. These practices grant an ideal opportunity to apply normative ethical theories in an evaluative context. The normative theories of interest here will be those of deontology’s duty-centric approach and utilitarianism’s focus upon happiness satisfaction as the highest degree of moral action. This approach will hopefully reveal the rotten core of Nestlà © Corporation’s past treatment of rational beings; whether or not it is the case that the company has truly changed these methods through time remains for another discussion. The present discussion, by focusing upon deontology and utilitarianism specifically, will examine the Kantian concepts of ends, utilitarian notions of value, and the evident lack of moral content backing Nestlà ©Ã¢â‚¬â„¢s actions. Nestlà © Corporation dates back to the mid-19th century when American businessmen joined with Henri Nestlà ©, a food developer, to create what would become the centerpiece of the company. Throughout the remainder of the 19th century, the company would continue to develop ground-breaking food products. Throughout the 20th century, the firm continued to innovate—growing ever larger through acquisitions and mergers. In recent times, Nestlà ©Ã¢â‚¬â„¢s line of products has revolved around a wide range of goods, including coffee, water, ice cream, infant foods, seasonings, frozen foods, refrigerated foods, pet foods, and nutritional products (Nestlà © Corporation). The organization’s stated

Monday, February 3, 2020

Relegion and marraige health Assignment Example | Topics and Well Written Essays - 500 words

Relegion and marraige health - Assignment Example Two related journals will be used to further substantiate the findings. Studying this topic will help us understand the influence religion has on marriage. The findings of religion health relationship have tremendously increased over the years. It will help in making informed decisions on how religion affects marriage and how to handle this situation. The questions asked are, The relationship between marriage and religion is complex in the context of church attendance during a week. Many of researches carried out have shown a deep relation as to why some marriages are not healthy due to one party in the marriage frequenting the church a lot in a week. Contrary to that, also different results have been derived from the same hypothesis. Some marriages have grown healthier because of frequenting the church (Marks). Irrespective of the religious affiliation, the results of the studies differ a little when it comes to the health of the marriage. It has been found that married couples that attend the church many times a week together have a healthier marriage than married couples who do not frequent the church together In this paper, the z-test was used to get these results. The test was used to sample thought of over 30 people. The valuable measures are H0: P = P0 against H1: P>

Sunday, January 26, 2020

Tim Berners Lee: The Inventor Of The Internet

Tim Berners Lee: The Inventor Of The Internet Many people have had a significant impact on the world of mass media that radically changed how the world communicates information. One example of someone who has done just that would be Tim Berners-Lee, who is best known for his innovation: The World Wide Web. Tim Berners-Lee has impacted the world of mass media in several ways. First, Tim Berners-Lee invented the World Wide Web. Second, since the World Wide Web was invented, it has radically changed the way that the people communicate. Third, the internet has revolutionized how the press gets information to the people. Finally, while the Internet has its advantages, it has had alot more than its share of controversy. First, Tim Berners-Lee invented the World Wide Web. The story behind the invention of the internet is an interesting one. It all began around 1980 while Tim Berners-Lee was working as a software engineer at the European Laboratory for Particle Physics in Geneva, Switzerland; also known as CERN. He wanted to figure out a new way to organize his notes in a brain-like way, but while improving upon the abilities of that occasionally memory-constrained organ and came up with a new way of doing it building a software program called Enquire (TIME). Using the ideas that he used to build Enquire and other ideas that were current at the time, he created another way of finding files on his computer: by creating a type of hypertext notebook that allows the text in a document to be linked to other files on the computer. He then thought about accessing materials on other computers. He then thought about opening his computer to not only his coworkers at CERN, but to the scientific community everyw here. By using this type of networking scheme by connecting individual computers together on a network, it would mean no centralized system. This would mean that the new network would have no trouble with scalability, which means that it could grow to infinity. Tim Berners-Lee then built a coding system that was easy to learn and use to build web pages. It is called HyperText Mark-up Language, also well known as HTML. It has become the most wildly used language that web developers or even normal people use to create web pages and sites. He then created e new set of protocols that allowed these HTML documents to be connected across the Internet called HyperText Transfer Protocol, also well known as HTTP. Soon after that, Tim Berners-Lee wrote the code for the first web browser, which allowed users around the world to access web pages on the internet. Once the World Wide Web debuted in 1991, the world of mass media changed forever as it brought order and clarity to the chaos that was cyberspace. The World Wide Web (the information-sharing model built for the internet that is the way accessing and sharing information on the internet) and Internet (the massive network of computers) experienced growth at exponential rates (The Difference). At one point, the number of internet users was doubling every 53 days (TIME). Clearly, Tim Berners-Lees inventions made a huge impact on the mass media industry. Second, since the World Wide Web was invented, it has radically changed the way that the people communicate. Since the Internet was first brought online, many social networking sites have radically changed how people, businesses and organizations communicate. One of those websites is Facebook. With Facebook, anyone could create a profile on the site and not only post their thoughts on their wall for friends to see and comment on, but also use instant messaging to talk to friends in real-time and even share photos and videos between friends or even everyone on Facebook. Facebook has evolved the way that people communicate in several ways. One example is how easy it is for anyone to click the Add Friend and reconnect with old friends. Another example is how the sheer number of people using Facebook affects the mass media, numbering in the hundreds of millions, possibly soon to be in the billions. Because of how many people use Facebook, the chances are good that anyone wanting to find old friends would find them on Facebook. Businesses who want to advertize would use Facebook because their ads would reach a very large amount of people. Organizations who create community pages or groups for a specific cause could also speak to a very large amount of people. Another great example is how Facebook is real time and very easy to update. Since Facebook is real time, people could keep their profiles current from anywhere with just seconds of work at a time, even from mobile devices such as cell phones. This also allows people to share events as they happen within seconds (Welcome)(NEWS). Clearly, Tim Berners-Lees invention allowed the social networking sites to form and they evolved the way that people communicate. The global nature of the Internet and the World Wide Web only helps to let sites like this expand on a huge scale. Third, the internet has revolutionized how the press gets information to the people. For hundreds of years, the newspaper has been the best known and well used source of information on current events. However, in recent years, its popularity has declined. Nowadays, 61% of citizens in the western world get their news from the Internet, compared to 17% who get their news from the newspaper. This could be for several reasons. One reason would be that people could access up-to-minute news on the internet at any time from any location if they want to because of the nature of the internet and the evolution of mobile devices that have the capability to access it. There is no need to go to a newsstand or store to buy a newspaper to read news that might be out of date. Another reason is that publishing a story on the internet is also much easier and less expensive than publishing it on printed media. Internet news could also have photos and video supporting the text on a new agencys website. Another reason would also be that the news is available to many more people due to the worldwide nature of the internet (What are)(Newspapers). Another mainstream format that the internet is quickly replacing would be television. Internet television and streaming video are supplying news in about the same format as television with full motion video. Internet video is also easier to set up and less expensive to put a video online or watch it (Internet). Clearly, Tim Berners-Lees inventions revolutionized how the press gets information to the people. Finally, while the Internet has its advantages, it has had alot more than its share of controversy. Since Tim Berners-Lee invented the internet, it has caused many controversies in the world. One key example of a significant issue in many countries that the internet has provided is the use of censorship to filter obscene materials and the worldwide nature of the network. Some countries, such as China have responded with a strict internet censorship scheme that regulates what types of content the people may read or write. In fact, the censorship scheme has been given the nickname The Great Firewall of China in popular culture because it blocks thousands of websites that the Chinese government feels are a threat to the country and society. It also affects the ability of the press to report current events freely and without restriction. This was especially a huge issue during the Beijing Olympics, where there were many foreign journalists on site. Another key issue that the internet has caused is the issue of privacy. One major breach of privacy that involves the internet would be Google Street View. Google Street View is part of Google Maps and it allows anyone to view an area as if they were standing on a street. Google uses specially modified vehicles with cameras that take pictures in every direction as the car drives along. These pictures are then uploaded to Google Maps and allow users to use them in addition to maps to look at an area. This has caused major privacy problems because there are several occasions when the vehicle takes photos of people on private property that do not wish to be photographed for various reasons. While Google does offer users the option of reporting individual images to request their removal from the web, that that would be after the fact and the image could have be saved by anyone prior to removal (15 Biggest). Clearly, Tim Berners-Lee has made a significant impact on the world of mass media because while his inventions created many advantages to how media is delivered to the people, it also creates massive controversies in the process. Tim Berners-Lee has had a significant impact on the world of mass media that radically changed how the world communicates information. His innovations that caused these changes are the World Wide Web and the Internet. Tim Berners-Lee has impacted the world of mass media in several ways. First, Tim Berners-Lee invented the World Wide Web. Second, since the World Wide Web was invented, it has radically changed the way that the people communicate. Third, the internet has revolutionized how the press gets information to the people. Finally, while the World Wide Web and the Internet has its advantages, it has had alot more than its share of controversy. Clearly, Tim Berners-Lee has impacted the world of mass media in many ways, positive and negative. Gaucher’s Disease: Types, Symptoms and Treatments Gaucher’s Disease: Types, Symptoms and Treatments New Treatment Plans Give Hope to Patients with Gaucher’s Disease Katherine Van: Gaucher’s disease occurs within individuals because they lack the enzyme glucocerebrosidase in the body, which is responsible for breaking down fatty substances called glucocerebroside. Consequently, large amounts of fatty substances are able to build up and stay in the liver, spleen, lungs, bone marrow and brain because of the damaged and lack of glucocerebrosidase. Hence, the disease is also called glucocerebrosidase deficiency. Any age group can be diagnosed with this disease, but studies show that there is a higher percentage of the disease in Eastern and Central European Jewish people.     Ã‚  Ã‚   There are many types of Gaucher’s disease. The first form is called non-neuronopathic Gaucher’s disease because it does not target and damage the central nervous system. The symptoms are: Thinning of bones Extreme bone pain and bone fractures Enlarged liver Enlarged spleen Low amounts of healthy red blood cells Excessive fatigue Vulnerability to bruising Low amounts of blood platelets Yellow spots in the eyes Regular nosebleeds The second type of Gaucher’s disease is neuronopathic and it can be life-threatening because it damages the central nervous system. Babies after three months of birth can be diagnosed with this form of Gaucher’s disease. Its symptoms are similar to the non-neuronopathic form, but it also includes: Brain problems, including dementia Severe inflexibility Seizures The last form of Gaucher’s disease is called perinatal lethal and it is the most severe type. In fact, most infants with perinatal lethal die after a few days of birth. The symptoms listed below: Extensive swelling due to fluid accumulation Dry and scaly skin Serious neurological problems Gaucher’s disease develops as a result of mutations in the GBA gene. The GBA gene is responsible for making glucocerebrosidase enzymes, which simplifies glucocerebroside molecules into sugars and smaller fat molecules. However, mutations in the GBA gene impact the ability of the enzymes to function properly. Consequently, the large amounts of fatty substances cause organ failure. Patients can be diagnosed with Gaucher’s disease because of an inheritance pattern called autosomal recessive. The parents must be carriers of a Gauchers genetic mutation in order for the children to have Gaucher’s disease. Nevertheless, there is only a 25 percent chance that their child will be diagnosed with the disease. In order to identify and track the progression of Gaucher’s disease within patients, a series of diagnosis and tests are used. Enzyme analysis uses blood tests to identify a patient’s levels of glucocerebrosidase. If Gaucher’s disease was active in the patient, there are low levels of glucocerebrosidase in the blood. On the other hand, carriers have enzyme levels between the affected and unaffected people who are not carriers. Another test is called the genetic mutation analysis and it tries to find mutations in the genes associate with Gauchers disease. However, not all of the genetic mutations involved in Gauchers disease have been identified; thus this test is used to help classify which type of Gauchers disease patients have. In order to measure the progression of the disease, dual energy X-ray absorptiometry (DXA), and magnetic resonance imaging (MRI) can also be used. DXA uses low energy X-rays to measure bone density, while MRI uses magnetic fields and rad io waves to create images of organs. MRI can show organ enlargement, such as the spleen or liver. In addition, doctors perform prenatal testing in pregnant women that are carriers of Gaucher’s disease to test if Gauchers disease is active in the fetus. Doctors will analyze the amniotic fluid or tissues from the placenta to complete the prenatal testing. Gauchers disease cannot be cured; it is only controlled or managed. The type of treatment given to patients varies depending on the type and severity of Gaucher’s disease and condition of patients. One treatment given is the enzyme replacement therapy, where replacement enzymes in liquid substances are injected into the veins of patients every two-weeks. This type of treatment is effective within individuals with non-neuronopathic Gaucher’s disease. Nevertheless, people may regularly experience an allergic reaction to the enzyme treatment. Another treatment method available is the bone-marrow transplantation. This is a surgical procedure that is used for severe cases of Gauchers disease, where damaged blood-forming cells are removed and replaced. However, this medical treatment is not as common as the enzyme replacement therapy because it has more threats and hazards. Lastly, medication can also be used to manage Gaucher’s disease. The oral medication miglustat ( Zavesca) is an effective drug that minimizes the build-up of the fatty substances in non-neuronopathic Gaucher’s disease. Nevertheless, the medication can cause side effects in the digestive system, such as diarrhea and, weight loss. Furthermore, the drug can also interfere with sperm production. In ladies, birth control is advised while using miglustat and for three months after they stop using the drug. In December 2001, Genzyme, a Sanofi Company completed a study to compare the effectiveness of a drug, Cerezyme, in two different dosage amounts in their patients with Gaucher’s disease. Both males and females ages 18 and older were eligible for study. Nevertheless, only patients with type 1, non-neuronopathic Gaucher’s disease were allowed to participate. There were multiple research centers that participated in the lab, including eighteen in the United States, one in Canada, six in Europe, and one in Brazil. During the study, 90 participants were randomized and placed into two groups. The first group of people received their monthly dose of Cerezyme in two infusions; one infusion per two weeks (Q2). The second group of individuals received their monthly dosage in one infusion every month (Q4). The progression of the effects of the drug on the Gaucher’s disease was monitored by measuring the hemoglobin values and platelet count of patients. Magnetic resonance ima ging and computer tomography were also used to explore any improvements in the patient’s liver and spleen conditions. Moreover, researchers tried to identify if the change in dosage reduced the symptoms of patients, such as fatigue, vulnerability to bruising and yellow spots in the eyes. Genzyme believed that patients who received one infusion every 2 weeks would show a more positive reaction towards their non-neuronopathic Gaucher’s disease because there was a longer period of time in between the monthly dosage sessions of Q4. Hence, this could cause a deficiency of all the replaced glucocerebrosidase at the end of the month. Conversely, Q2 would be more stabilized because the enzyme glucocerebroside would be replaced every two weeks. In theory, by the end of each month, only half of the enzyme glucocerebroside would be deficient. Similarly, the findings of the lab, displayed in table one, showed that 80.8% of the participants of Q2 Cerezyme showed clinical success, whereas there was only 63.2% of clinical success within individuals using Q4 Cerezyme. Hence, Q2 was a better drug frequency in terms of safety and efficacy. Q2 Cerezyme Q4 Cerezyme Number of Participants Analyzed 26 57 Number of participants with Clinical Success 21 36 Proportion of participants with Clinical Success 80.8% 63.2% Table 1: Number of Participants with Clinical Success after the Completion of the Clinical Trial The chart above portrays the number of participants that showed improvements in their Gaucher’s disease in comparison to their condition before the clinical trial. For example, some participants noticed a reduction of symptoms, such as extreme tiredness, bruising, yellow spots in the eyes, and nosebleeds. As well, there were some improvements in hemoglobin values, platelet count, and liver and spleen conditions. A similar lab was conducted to test the efficacy of two dosage amounts in an enzyme replacement therapy on February 1, 2007. The global specialty biopharmaceutical company, Shire, wanted to test VPRIV, a hydrolytic lysosomal glucocerebrosidase-specific enzyme, that was used in long-term enzyme replacement therapy for patients with type 1 Gaucher’s disease. The controlled variable of the study were the 45 and 60 U/kg dosages of VPRIV, also known as velaglucerase alfa (GA-GCB), given to patients with type one Gaucher’s disease. Shire also used random trials to divide the participants into two groups that received the dosage every other week. Nevertheless, one group received 45 U/kg and the other group received 60 U/kg of VPRIV. Ages two and older of both genders were allowed to participate in the study. The duration of treatment for each patient was 12 months, where the first patient enrolled into the study on January 11, 2007, and the last patient participated in the res earch project on April 8, 2008. The progression of the effects of the drug on Gaucher’s disease was monitored by measuring the hemoglobin values and platelet count of patients. Magnetic resonance imaging and computer tomography were also used to explore any improvements of the patient’s liver and spleen conditions. Shire believed that 60 U/kg of VPRIV was a better treatment towards the non-neuronopathic Gaucher’s disease, assuming that VPRIV was safe and efficient, because there were more artificial enzymes. The data collected in table two supported their hypothesis as the average change of baseline of Gaucher’s disease was better in the twelve participants that used 60 U/kg of VPRIV every other week. A baseline is the initial amount of a substance where the final amount is compared to. A baseline is also referred to as the reference point. The chart supports Shire’s hypothesis as the spleen and liver volumes of VPRIV 45 U/kg patients decreased and hemoglobin and platelet concentrations increased towards a more normalized size or amount. Nevertheless, the research is still continuing and the data released is not fully up to date. VPRIV 45 U/kg, Every Other Week VPRIV 60 U/kg, Every Other Week Number of Participants Analyzed 13 12 Average Change of Baseline of Spleen Volume (units: Percent body weight) -1.87 -1.92 Average Change of Baseline of Liver Volume (units: Percent body weight) -0.30 -0.84 Average Change of Baseline of Hemoglobin Concentration (units: g/dL) 2.429 2.438 Average Change of Baseline of Platelet Counts (units: x10^9/L) 40.92 50.88 Table 2: Change of Baseline of Gaucher’s Disease in Participants After 12 Month Treatment The chart above portrays the average change of baseline of spleen volume, liver volume, hemoglobin concentration and platelet counts for two groups of patients; those who received 45 U/kg of VPRIV, and other who received 60 U/kg of VPRIV every other week. Negative values indicate a decrease in size, whereas positive values indicate an increase in size. The data was collected by using magnetic resonance imaging and analyzing participates’ blood tests. Overall, studies continue to occur in order to find more effective treatments for individuals suffering from Gaucher’s disease. The severity of this disease may vary from patients, but in general, the disease is very harmful as it can lead to deaths in young age groups. Gaucher’s disease attacks important organs in the body, such as the liver, spinal cord, heart and brain, and prevents the organs from functioning properly. Nevertheless, the disease only occurs due to genetics and the positive research projects conducted on Gaucher’s disease will continue to bring hope in humans. References http://www.convertunits.com/info/dl http://www.nlm.nih.gov/medlineplus/ency/article/003647.htm http://www.cancer.ca/en/cancer-information/cancer-type/childhood-cancer-information/supportive-care/symptom-and-side-effect-management/low-platelet-count/?region=nu http://www.lilly.com/products/patient-safety/providers-role/Pages/adverse-event.aspx http://www.drugs.com/monograph/cerezyme.html http://www.mayoclinic.org/diseases-conditions/gauchers-disease/basics/coping-support/con-20031396 http://ghr.nlm.nih.gov/condition/gaucher-disease http://www.shirecanada.com/en/default.aspx http://www.vpriv.com/about-vpriv/ http://clinicaltrials.gov/ct2/show/results/NCT00430625?term=gaucher+diseaserank=13sect=X012 http://clinicaltrials.gov/ct2/show/NCT00364858?term=Gaucher%27s+Diseaserank=3